In September 2023, the FDA flagged injectable GHK-Cu as high-risk
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The buy GHK-Cu peptide decision is supported by over five decades of peer-reviewed research demonstrating consistent biological activity across multiple tissue types and research models
The risk, however, lies less with the molecule itself than with the quality of the preparation and the conditions of administration: a cluster of seven cases of endotoxin poisoning was described after infusions prepared from contaminated raw material not intended for intravenous use (Johnstone et al., Epidemiology and Infection 2018, PMID 29673413)
Incorporating GHK-Cu copper peptide serum with microneedling is more than just a skincare routine
Thus, it is tempting to speculate that its expression in mature erythrocytes might be also associated with selection of a cell death pathway