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AOD-9604 failed Phase 2 not due to adverse events but because the mean fat loss versus placebo, while statistically significant, was too modest for a standalone obesity treatment

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91 In a placebo-controlled trial in 228 men with infertility, 200 mg CoQ10 daily for 26 weeks resulted in greater improvements in sperm concentration, motility, and morphology, as well as a reduction in FSH and increase in inhibin B levels

4.5 mg weekly in trials

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