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Freezing destroys peptides

They often show the symptoms of vitamin B12 deficiency, but when they get tested their vitamin B12 levels are normal

Pharmaceuticals 13:38 Herndon TM, Deisseroth A, Kaminskas E, Kane RC, Koti KM, Rothmann MD, Habtemariam B, Bullock J, Bray JD et al (2013) US Food and Drug Administration Approval: carfilzomib for the treatment of multiple myeloma FDA approval summary of carfilzomib

J Am Chem Soc 137:42154222 Wu H, Huang J (2018) Optimization of protein and peptide drugs based on the mechanisms of kidney clearance

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Severe deficiency : Weekly or biweekly injections may initially be required to correct anemia and neurological symptoms