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This is not a complete list and includes frequently reported adverse events

Serious adverse effects requiring clinical vigilance include: Lactic acidosis : A rare but potentially fatal complication of metformin, particularly in patients with renal impairment (eGFR 10%), symptomatic hyperglycemia, diagnostic uncertainty, or recurrent hypoglycemia

Penagarikano O, Lazaro M, Lu X, Gordon A, Don H et al

Q., & Liu, Q

Reconstitution in liposomes of the functionally active human OCTN1 (SLC22A4) transporter overexpressed in Escherichia coli

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