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One third of patients with IBD and active disease have iron deficiency, which has a significant impact on quality of life
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NAD (Nicotinamide Adenine Dinucleotide) is a coenzyme made up of two nucleotides that join through their phosphate groups
The intranasal route is biologically required to bypass the blood-brain barrier effectively
However, the effect of oral vitamin B 12 varies among patients (13), and the available randomized controlled trials comparing the two treatment regimens are considered to be of low quality (14)
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