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10.1152/ajpheart.00758.2006 [DOI] [PubMed] [Google Scholar] Yoboue ED, Sitia R, Simmen T (2018) Redox crosstalk at Endoplasmic reticulum (ER) membrane contact sites (MCS) uses toxic waste to deliver messages

89,90 In addition to classical models in which CSCs arise from transformed tissue-resident stem cells, recent evidence suggests that differentiated tumor cells can reacquire stem-like properties under certain conditionsa phenomenon referred to as cellular plasticity