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Regular use of insecticidal products (flea products) on the cat or fly sprays within the household (7,9,15)

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Further understanding of the complex mechanisms that regulate metabolic homeostasis and how these become dysregulated during metabolic diseases, which are currently a major global burden, will likely lead to the development of new highly desirable more effective therapeutic strategies to combat metabolic diseases such as T2D

The approved schedule is: Days 1 to 30: 1.5mg once daily Days 31 to 60: 4mg once daily Days 61 to 90: 9mg once daily Day 91 onwards: 25mg once daily (maintenance dose) The maintenance dose of 25mg is taken once daily for the duration of treatment

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The results shown in Fig