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Patients who lose more than 8 pounds in the first two weeks are primarily shedding water weight and glycogen

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Dolotov OV, et al

In conditions of nutrient depletion, ULK1 is activated, which leads to phosphorylation of the components of the Class III PI3K vacuolar protein sorting 34 (VPS34) protein complex, resulting in the formation of autophagosome and promoting the autophagy flux [255]

Neutralises free radicals

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