Extracellular Matrix (ECM) Synthesis: The copper ion is a vital cofactor for lysyl oxidase, an enzyme required for the structural cross-linking of collagen and elastin
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23, Rome: Food and Agriculture Organization of the United Nations
MOTS-c has been shown in preclinical studies to improve insulin sensitivity, increase glucose utilization in skeletal muscle, and protect against age- and diet-related metabolic dysfunction
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Importantly, preclinical studies showed that weight reduction occurred particularly in abdominal adipose tissue, the visceral fat depot most strongly associated with metabolic health risks