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GLP- 1 receptor activation has longer-term consequences, such as increased b cell proliferation and neogenesis along with cytoprotective (non-insulinotropic) effects [45,46,47,48,49,50,51]

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Van Mierlo LD, Meiland FJ, Van Hout HP, Droes RM

Semaglutide 2.4 mg once weekly may not work well for certain populations, and the weight loss from bariatric surgery varies greatly (32% of patients with T2DM achieve 5% weight loss with semaglutide 2.4 mg) [112]

The total scores on the BPRS and the CGI-S scores decreased, not significantly, at one, two, and three months from baseline