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This is a disease-modifying therapy. The bottom line, he added, is that we have a new treatment for PAD, and we just have to see how Health Canada, the global guidelines and others incorporate this into their practice.

There are other things that we'll screen for in terms of risk

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Evidence supporting this raft-mediated mechanism is that cholesterol extraction or impaired sphingolipid synthesis reduces apical transport in epithelial cells (Hansen et al., 2000