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What structural differences actually matter

Characteristically, the terminal ileum is devoid of any pigment uptake as seen here

Since then, different animal models have been used to demonstrate its important roles in metabolic disorders

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Ahrn B, Simonsson E, Larsson H et al (2002) Inhibition of dipeptidyl peptidase IV improves metabolic control over a 4 week study period in type 2 diabetes