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Nanogels provide another flexible platform

Since HNMT (the intracellular histamine-degrading enzyme) requires SAMe, impaired methylation can slow histamine clearance, especially in tissues like the brain and airways, where HNMT is the primary clearance pathway

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Clinical assessment and full blood count showing macrocytic anaemia are also important, though neurological symptoms can occur without haematological changes

It plays a vital role in transporting fatty acids into the mitochondria, the body's energy powerhouses

Data from 76 RCTs with 103,371 patients were included in the meta-analysis