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In addition, increased p53 expression inhibits the expression of the system xc SLC7A11, resulting in reduced uptake of cystine, decreased GSH peroxidase activity, reduced cell antioxidant capacity, and increased sensitivity of cells to ferroptosis (Kang et al., 2019)

The bound copper is from inorganic copper sources, not animal-derived

Cells show delayed replicative senescence and extended lifespan in culture

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however, immunogenicity may be hampered owing to the natural immune barriers present at these sites

Severe lack can lead to anemia , digestive issues, and brain damage