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It remains to be determined whether boosting complimentary routes with exogenous substrates, such as citrate, or genetic/pharmacological interventions to increase ME1 or IDH1 levels and/or activity, is sufficient to counteract the excessive oxidative stress and hemolysis seen in G6PD def erythrocytes

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This medication works by enhancing insulin secretion in response to elevated glucose levels, suppressing glucagon release, slowing gastric emptying, and reducing appetite through central nervous system pathways

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