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The cytosolic glutathione buffer is normally highly reduced

A fundamental feature of aging is a decline in mtDNA transcription and repair capacity which can lead to mitochondrial malfunction and set in motion a vicious cycle of enhanced ROS production ( An increase in oxidative stress, observed as increased oxidant and reduced antioxidant levels in serum, has frequently been associated with HAART in patients (Mandas et al., 2009)

Ben Anes A, Ben Nasr H, Fetoui H, Bchir S, Chahdoura H, Yacoub S, Garrouch A, Benzarti M, Tabka Z, Chahed K

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It supports the orthodontists plan

Overall, this will improve the ability to track project progression and commercialization success