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GSH Metabolism and NAC Supplementation Whereas NADPH-dependent GSH regeneration is one way by which the GSH pool can be restored, other metabolic pathways are capable of generating GSH

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Tablets must be swallowed whole for sustained release guanfacine ER 1 mg daily increasing by 1 mg/week to max 0.12 mg/kg/day or 4 mg/day (6-12 years) or 7 mg/day (13-17 years) Originally maximum dose was 4 mg day but doses up to 7 mg in adolescents are tolerated and effective

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