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Risk factors that should prompt consideration of B12 deficiency include advancing age (reduced stomach acid production), strict vegan or vegetarian diets, pernicious anaemia, gastrointestinal surgery (particularly gastric bypass or ileal resection), long-term use of certain medications (metformin, proton pump inhibitors, H2-receptor antagonists), nitrous oxide exposure (including recreational use), and conditions affecting the gut such as Crohn's disease or coeliac disease

Pros: fewer reconstitution events

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He teamed up with his fellow Tatiana Hathway, MD, and several other trainees to analyze the records of 17,000 Mass Eye and Ear patients treated since the FDA first approved Ozempic