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It is not FDA-approved, and no standardized medical dosing protocol exists

Heart failure Analysis of myocardial samples from patients with ischemic and dilated cardiomyopathy in the terminal stage of heart failure, as well as from heart donors without heart disease, found that the downregulation of multiple mitochondrial quality control genes, including LONP1, is closely related to heart failure [63]

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Yuan, L., Yi, P., Wang, G., Tan, S., Huang, G., Qi, L., Jia, Y., & Wang, F