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Lancet 2022;399(10327):824-36 Lieberman JA, Stroup TS

Wang Y, Li L, Yang M, Liu H, Boden G, Yang G

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LC-MS/MS acquisitions For the discovery cohort, untargeted analysis samples were analyzed by nanoLC/MSMS using a Dionex UltiMate 3000 nanoRSLC liquid chromatography system (Thermo Fisher Scientific) interfaced to an Orbitrap Fusion Tribrid mass spectrometer (Thermo Fisher Scientific, San Jose, CA,USA) equipped with a nanoelectrospray ion source

Semaglutide: Albumin-Binding Powerhouse Semaglutide is a second-generation GLP-1 receptor agonist originally developed for type 2 diabetes and now widely used for weight loss

They are provided as Supplementary Material