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For patients without specific contraindications, the documented benefits of effective weight loss likely outweigh the unconfirmed thyroid concerns

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The increasing prevalence of DM, ASCVD, and CKD necessitates therapeutic strategies that are not only effective and safe but also accessible and scalable

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After vigorous shaking of the tubes for 10 min using a vortex mixer, the mixture was centrifuged at 3,000 rpm at 0 C for 15 min to separate the two phases