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The left ventricular anterior wall (LVAW) and posterior wall (LVPW) thickness and the internal diameter (LVID) were measured in both the diastolic stage and systolic stage

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The authors also performed in silico investigations for genomes of 25 fish species, mostly teleosts, and largely confirmed the observations from the common carp study regarding division into subgroups and conservation of synteny and concluded that all teleosts gpr40L genes appear closest to the human GPR43 and that the teleost grp40L family originated from a single ancestral gene multiplied by tandem duplication and later divergence

3a-b), and mutations in the DQY polar motif largely decreased potencies of both G protein and -arrestin signaling of fentanyl and morphine, indicating that the DQY polar motif was crucial for OR activation

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