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Then, aspartate is used for nucleotide biosynthesis

For example, the ROS hydrogen peroxide, which reduced glutathione directly neutralizes, is a form of ROS that also causes significant inflammation in the body

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FIGURE 5 The Effect of GSTP1 on AQ-QI- and DEAQ-QI-Induced Alteration on Cellular GSH Homeostasis To evaluate whether cellular GSH homeostasis was affected by QIs, and whether GSTP1 did influence the effects, concentrations of intracellular GSH and GSSG were quantified following exposure to synthetic AQ-QI and DEAQ-QI

Medical Science Monitor 22:4175-4189