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This triple agonist has demonstrated superiority to dual coagonists (GLP-1R/GIPR) and mono-agonists (GLP-1) in reducing body weight (reduction of 25% in 4 weeks), improving glycemic control, and reducing hepatic steatosis in rodent models

Animal models have demonstrated how SFN can alter microbiota composition, correlating with behavioral improvements, and suggest that targeting gut bacteria may be one of the mechanisms of benefit

These compounds do not form cross-links and cannot further bind to proteins 81

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