Patients taking concurrent medications that affect electrolyte balance (such as diuretics) require particularly careful monitoring
The medications work through entirely separate biological pathways and can be used together when clinically appropriate
- each monomer has at least one redox-active Cys couple (in front of the FAD) and a redox-active Sec-Cys couple in the C-terminal arm
doi: 10.1016/j.fertnstert.2007.07.1290 102 ThomsonRBuckleyJNoakesMCliftonPNormanRBrinkworthG
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Each step assumes at least four weeks at the previous dose with side effects you can live with, and providers often hold a dose longer than four weeks by design