Seiwerth et al., Frontiers in Pharmacology (2021) and Xing et al., Int J Mol Sci (2021)
It is indicated for the treatment of premenopausal women with acquired, generalized hypoactive sexual desire disorder (HSDD) as characterized by low sexual desire that causes marked distress or interpersonal difficulty and is NOT due to: Caffeine 3-6 Caffeine, structurally a xanthine, is a central nervous system and respiratory stimulant
Increased physical activity: Patients experiencing improved glycemic control and weight loss often increase their physical activity levels
where possible, take oral medicines at least one to two hours before or several hours after glucomannan Some botanical ingredients , including green tea, may interact with anticoagulants such as warfarin The absence of a prescription requirement does not mean a product is without risk
Freezethaw: Avoid repeated freezethaw cycles of the reconstituted solution
Steady-state is reached after 4 to 5 weekly doses, consistent with the roughly 1-week half-life (accumulation ratio of approximately 3 to 4)