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16 The primary 3-point MACE endpoint did not achieve statistical significance (HR, 0.93

Topical tranexamic acid has been used alone and in conjunction with modalities to increase uptake, including intradermal injection, micro-needling, and fractionated CO2 laser

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For extended storage, it is recommended to store it at -80C

Decreased activity of the mitochondrial respiratory chain was reported in overweight/obese patients with NASH compared to controls [97, 98], and alterations in mitochondrial ultrastructure have been observed prior to NAFLD development in the Otsuka LongEvans Tokushima Fatty rat [99] as well as in patients with steatosis preceding progression to NASH [100]