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Wallin BG, Kunimoto MM, Sellgren J

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It has also been examined in preclinical work involving immune associated pathways and cytokine profiling

Nevertheless, lesional CTLs are not the only cells that activate the CCL5CCR5 axis: In vitiligo, CCR5 expression is elevated on regulatory T cells (Tregs), indicating that (dysfunctional) Tregs may be involved in skin depigmentation

[22][24] In an SMA mouse model, VPA treatment resulted in improved gross motor function, larger evoked motor potentials, less degeneration of spinal motor neurons and improved neuromuscular junction innervation in treated animals compared to age-matched controls [24]

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