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Effects of Tirzepatide on Lipid Profile: A Systematic Review and Meta-Analysis

Gastroenterology 162 , 548561.e4 (2022)

This small molecule is a potent and selective non-competitive inhibitor of NNMT

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Biol Mar Mediterr 25(1):212213 Garrabou J, Gmez-Gras D, Ledoux JB, Linares C, Bensoussan N, Lpez-Sendino P, Bazairi H, Espinosa F, Ramdani M, Grimes S, Benabdi M, Souissi JB, Soufi E, Khamassi F, Ghanem R, Ocaa O, Ramos-Espl A, Izquierdo A, Anton I, Rubio-Portillo E, Barbera C, Cebrian E, Marb N, Hendriks IE, Duarte CM, Deudero S, Daz D, Vzquez-Luis M, Alvarez E, Hereu B, Kersting DK, Gori A, Viladrich N, Sartoretto S, Pairaud I, Ruitton S, Pergent G, Pergent-Martini C, Rouanet E, Teixid N, Gattuso JP, Fraschetti S, Rivetti I, Azzurro E, Cerrano C, Ponti M, Turicchia E, Bavestrello G, Cattaneo-Vietti R, Bo M, Bertolino M, Montefalcone M, Chimienti G, Grech D, Rilov G, Tuney KI, Kizilkaya Z, Eda TN, Gerovasileiou V, Sini M, Bakran-Petricioli T, Kipson S, Harmelin JG (2019) Collaborative Database to Track Mass Mortality Events in the Mediterranean Sea

Researchers should follow a gradual titration approach to optimize results