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For now, the Medicare GLP-1 Bridge gives clinicians and patients an 18-month window of access that did not exist before, and the task for prescribers is to use it wisely while advocating for a durable solution beyond 2027.

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Affordability and Global Representation Challenges The authors emphasized that widespread adoption must consider social and economic factors such as affordability, insurance coverage, and accessibility to prevent widening existing health inequalities

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Discussion By taking advantaging of multiple transgenic mouse models (adipocyte-specific leptin overexpressing mice