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AOD-9604 works in the body on adipose tissue, also known as body fat tissue

Competitive inhibition of MDH in the presence of high meso -tartrate concentrations was concluded (Supplementary Figure S4)

Le, A., & Dang, C

Safe: The site typically has no critical structures nearby

This last point is legally significant because it undermines the argument that the vision loss is caused by underlying diabetes rather than the medication itself

169 Therefore, the investigators have suggested switching to a non-oral contraceptive option or adding a barrier method of contraception for 4 weeks after tirzepatide administration is initiated or if the dose is substantially increased