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The most effective approach addresses both layers: BHRT restores the hormonal foundation, and targeted peptide therapy optimizes the systems that hormones alone dont fully restore
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In: The 7th Medichem Congress, Gera, 11-15 September, 1979
doi: 10.1074/jbc.M112.420224 140 LiaoF.LiA.XiongM.Bien-LyN.JiangH.ZhangY.et al
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For example, these mediators, increase RANKL expression in stromal/osteoblastic cells or by sensitizing precursors to RANKL stimulation ( Estrogen plays a critical regulatory role in osteoclastogenesis primarily through modulation of the RANKRANKL signaling pathway
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