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These results were compatible with the detrimental role of AMPK in beta cell survival in previous reports 32,33,34,35,36

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In terms of oxidative stress, levels of malondialdehyde (MDA), 8-iso-prostaglandin F2, and 8-hydroxy-2deoxyguanosine (8-OHdG) were significantly reduced, implying that GLP-1RAs reduce lipid peroxidation and oxidative DNA damage

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This means your dose can increase as your provider adjusts your treatment without your monthly cost changing