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Similar content being viewed by others Main Cells that undergo senescence stably exit the cell cycle and display distinct phenotypic changes, which include the production of a bioactive secretome (the senescence-associated secretory phenotype (SASP)), reprogramming their metabolism and becoming more resistant to cell death 1

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These case reports generally involve the overdose of subjects weighing less than 50 kg and the majority of these case reports concern dose miscalculation in paediatrics