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It is noteworthy that metformin was most utilised agent during this period

It has been shown that mitochondria-free axon terminals of hippocampal or cortical neurons accumulate more Ca 2+ in response to repetitive stimulation, which promotes increasingly more SV release [55, 56]

Copper delivery: GHK-Cu carries bioavailable copper into tissues where it can support enzymes involved in collagen cross-linking and repair

Each experimental group consisted of 8 mice (n = 8 per group)

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