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1, Supplementary Figure S1)
It has been shown using various atherosclerosis animal models that GLP-1RA therapy is associated with a reduction in atherosclerotic plaques, prevention of aorta intima-media thickening, improvement in vascular endothelial function, reduction of the necrotic zone and an increase of the fibrous component in the plaque and plaque stabilisation
All Specific pathogen-free C57BL/6 male mice were purchased from SLAC Laboratory Animal Co., Ltd
GLP-1 agonists appear to influence reward-related pathways beyond appetite control