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Start of the PI3K/Akt and MAPK/ERK pathways can be detected within 15-30 minutes of use in research models

C., Haque, G., Thomas, B., Stone, A

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However, recent evidence suggests that non-12-OH FXR-antagonistic BAs in humans exert similar metabolic effects observed for those non-12-OH FXR-antagonistic BAs in rodents 29

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