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Patients should also be alert for signs of improper storage that may precede visible discoloration, including exposure to freezing temperatures, direct sunlight, or heat sources above 86F (30C)

doi: 10.1016/j.freeradbiomed.2010.01.035 43 CasarenoR

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Cytoplasmic Alteration (Figure 44) Synonyms Cytoplasmic alteration, cytoplasmic change, granular change, granular degeneration, hyaline degeneration, glycogen accumulation