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Increased CHAC1 levels induce ferroptosis and inhibit GC cell proliferation and survival, indicating that targeting the ATF4/CHAC1 axis could be a promising strategy for ferroptosis-based cancer therapy

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In particular, a lower ribose biosynthesis rate might mask folate deficiency or confer methotrexate resistance, with potentially broad implications in metabolic disorders and cancer therapy

Industry groups argued that the FDA's review did not reflect more recent scientific data on BPC-157 and other compounds, including results from human studies submitted ahead of time

[DOI] [PubMed] [Google Scholar] 26.Rattanakaemakorn P, Phusuphitchayanan P, Pakornphadungsit K, Thadanipon K, Suchonwanit P

Glutathione: Antioxidant, detoxification