ADVERSE REACTIONS Most common adverse reactions (incidence 20% in at least 1 indication) included skin hyperpigmentation, injection site reactions, nausea, headache, diarrhea, abdominal pain, vomiting, depression, and spontaneous penile erection
Retinal experts do recommend obtaining a baseline eye exam and considering closer follow-up of patients on GLP-1RAs within the first 12 to 18 months of starting the drug, particularly for those who have more severe DR at baseline, high baseline HbA 1c percentage, and rapid improvement in glycemic control similar to the characteristics of the patients enrolled in SUSTAIN 6
M.De CataP.et al (2014)
Youll see the full effect in around 10 days
Improved Insulin Sensitivity Improved Insulin Sensitivity As estrogen levels decline during perimenopause, insulin resistance often increases , making it easier to gain weight and harder to lose it
But GLP-1 receptor agonists exploded in popularity after researchers noticed people on the medications had lost significant amounts of weight