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The selectivity for beta-3 receptors explains the favorable safety profile compared to non-selective beta agonists that cause cardiovascular stimulation and other systemic effects
N, N-diisopropylethylamine (DIPEA), Protease K, 30% hydrogen peroxide (H 2 O 2 ) solution, and Ethylenediamine dihydrochloride were purchased from Shanghai Aladdin Biochemical Technology Co., Ltd
More recently, ABHD15, initially identified as a 47 KDa AKT substrate, has been shown to mediate the effects of insulin on lipolysis (122, 123) by stabilizing PDE3B (124, 125)
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