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Adding a second compound while still experiencing significant adverse effects from the first makes it impossible to isolate which agent is responsible for new or worsening symptoms
People experiencing this side effect should consult their cancer care team to find solutions and help maintain adequate nutrition during treatment.
Investigating Mechanisms in Humans: While preclinical studies have elucidated many molecular pathways, further research is needed to confirm if these mechanisms operate identically or with similar magnitude in human physiology
This methodology was then applied to the case of Turin, where the CRFS delineation was analyzed across various potential scales (City of Turin, Metropolitan City of Turin, Piedmont Region, Italian North-West industrial triangle of Genoa, Milan and Turin), reflecting the interplay of urban and rural relations in multiple fields
None of which replace Phase 2 safety and efficacy data in human subjects
