The enzymes that normally eliminate radical oxygen species are especially vulnerable
Accordingly, rebound in the periconception period should be viewed as a clinically plausible translational concern rather than as a phenomenon established specifically in women with PCOS
Similar content being viewed by others Log in or create a free account to read this content Gain free access to this article, as well as selected content from this journal and more on nature.com or Abbreviations GSH: reduced glutathione GSSG: glutathione disulfide GS: thyil radical ROS: reactive oxygen species RNS: reactive nitrogen species RS: reactive species -GCS: -glutamylcysteine synthetase GPX: glutathione peroxidase GR: glutathione reductase GST: glutathione S -transferase GSNO: nitrosoglutathione G6PD: glucose-6-phosphate dehydrogenase NAC: N -acetyl-L-cysteine NO: nitric oxide protein-SSG: protein glutathionylation protein-SNO: protein nitrosylation References Galluzzi L, Maiuri MC, Vitale I, Zischka H, Castedo M, Zitvogel L et al
Ducrest A, Amacker M, Mathieu YD, Cuthbert AP, Trott DA, Newbold RF, Nabholz M, Lingner J (2001) Regulation of human telomerase activity: repression by normal chromosome 3 abolishes nuclear telomerase reverse transcriptase transcripts but does not affect c-Myc activity
Mice also developed skin irritation and graying of the fur that was reversed with pantothenic acid administration
In a glutathione push, a nurse delivers glutathione intravenously by injecting it directly into an existing IV line using a syringe
