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Wearing a wide-brimmed hat, large sunglasses, and sun-protective clothing is also an effective way to enhance your sun protection and prevent melasma from worsening or returning

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This innovative strategy leverages cell membrane-derived surface properties to confer immune-evasive capabilities, prolong bloodstream retention, and enable tissue-specific cellular internalization, thereby addressing critical limitations in conventional nanodrug delivery systems [204,205,206,207,208]

During this process, up to 80% can be lost

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