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The human IR exists in two isoforms (A and B), which differ by 12 amino acids at the C-terminus of the A-chain due to alternative splicing of exon 11 (A isoform: -exon 11

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BMJ 320(7238):827832 Jiang W, Li W, Cheng J, Li W, Cheng F (2023) Efficacy and safety of liraglutide in patients with type 2 diabetes mellitus and severe obstructive sleep apnea

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Liraglutide works by mimicking the natural GLP-1 hormone, which signals fullness, regulates gastric emptying, and influences hunger pathways in the brain