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A pig pharmacokinetic study reported confusing oral bioavailability values exceeding 100%, which the authors attributed to high data variability

doi:10.1016/j.cellimm.2005.10.002 Arshad SH, Karmaus W, Raza A, et al

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The recurring findings were that the substances are not well characterised, that human evidence of effectiveness is thin or absent for the proposed routes of administration, and that immunogenicity risk has not been assessed

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Bajaj HS, Welch M, Shah P, et al