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[28] [29] Fezolinetant requires baseline and periodic liver function monitoring and is contraindicated in significant hepatic impairment

No pharmacokinetic interaction has been established between semaglutide and common SSRIs, but the shared appetite-suppressive effects of some antidepressants (notably bupropion) and GLP-1 agonists can produce additive nausea in the first four to eight weeks of concurrent use

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Three GLP-1 medications will be covered under the Medicare GLP-1 Bridge Program: Who Is Eligible