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Treatment requires individual assessment and monitoring for efficacy and safety

Diabetic peripheral neuropathy (DPN) is one of the complications of diabetes mellitus and is caused by neuron injury induced by hyperglycemic circumstances

Their mechanisms diverge on several key fronts: GHK-Cu has documented antioxidant effects and MMP/TIMP modulatory activity, while retinoids primarily drive epidermal turnover and reduce UV-induced MMP activation

This controlled heating process activates the bodys natural healing response, encouraging collagen remodeling and gradually lifting and tightening loose skin

doi: 10.1016/j.biopsych.2015.02.020 72 HamonM.BlierP