Figure 14 Statements Data availability statement The data presented in the study are deposited in the OMIX repository, accession number OMIX007423
in contrast, neurons express mainly PKM1, explaining why cabergoline stimulation did not alter GSH levels in neurons but increased GSH synthesis in astrocytes (Fig
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Studies have also reported that DSIP stimulates the release of luteinising hormone (LH) and somatotropin (growth hormone), while inhibiting somatostatin indicating a broader endocrine regulatory role that extends beyond the stress axis
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SURMOUNT-OSA: Tirzepatide and obstructive sleep apnea The SURMOUNT-OSA trial (Malhotra et al., NEJM 2024, NEJMoa2404881, PMID 38912654) evaluated tirzepatide in adults with moderate to severe obstructive sleep apnea and obesity, in two parallel populations: subjects not receiving continuous positive airway pressure (CPAP) and subjects receiving CPAP at baseline