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Environmental factors as the main hormonal disruptors of male fertility

It tends to lose water more easily and may not have enough of the lipids it needs to stay strong

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For systemic effects, injection may be preferred

Differential changes in PKLR in males (decreased) and females (increased) could have significant functional consequences in liver since glycolytic inhibition (such as by decreases in PKM2) has been suggested to promote the pentose phosphate pathway to generate higher levels of NADPH

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